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Davis Drug Guide PDF. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Using this medicine with any of the following is not recommended. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco. Isocarboxazid, like the other MAOIs, can cause a variety of side effects apart from the food interactions described above.

Isocarboxazid interactions

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Isocarboxazid is predicted to increase the risk of antimuscarinic adverse effects when given with doxylamine. Manufacturer advises avoid. Severity of interaction: Isocarboxazid is predicted to increase the risk of antimuscarinic adverse effects when given with cetirizine. Manufacturer advises avoid.

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A dangerous drug interaction could occur. MAO inhibitors include linezolid, methylene blue injection, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, and others.

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Isocarboxazid interactions

Classification. Therapeutic: antidepressants.

Isocarboxazid interactions

MAO inhibitors include linezolid, methylene blue injection, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, and others. Some young people have thoughts about suicide when first taking an antidepressant. Eating tyramine while you are taking isocarboxazid can raise your blood pressure to dangerous levels which could cause life-threatening side effects. Isocarboxazid may impair your thinking or Do not use isocarboxazid if you have used another MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include linezolid, methylene blue injection, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, and others.
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Isocarboxazid interactions

Severity of interaction: Do not use isocarboxazid if you have used another MAO inhibitor in the past 14 days.

Isocarboxazid is used to treat symptoms of depression that may include anxiety, panic, or phobias. Isocarboxazid is usually given after other antidepressants have been tried without successful treatment of symptoms.
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Isocarboxazid is a non-selective hydrazine monoamine oxidase (MAO) inhibitor. In vivo and in vitro studies demonstrated inhibition of MAO in the brain, heart, and liver. The mechanism by which MAO inhibitors act as antidepressants is not fully understood, but it is thought to involve the elevation of brain levels of biogenic amines.


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Find information on Isocarboxazid (Marplan) in Davis’s Drug Guide including dosage, side effects, interactions, nursing implications, mechanism of action, half … Description: Isocarboxazid, a hydrazine derivative, is an irreversible inhibitor of both monoamine oxidase types A and B. It increases endogenous concentrations of epinephrine, norepinephrine, dopamine, and serotonin through inhibition of the enzyme, monoamine oxidase, responsible for the breakdown of these neurotransmitters. DGIdb, The Drug Gene Interaction Database, is a research resource that can be used to search candidate genes or drugs against the known and potentially druggable genome.